HL7 Europe has published Base and Core FHIR Implementation Guides version 2.0.0
Brussels, 28 April 2026 — HL7 Europe has published version 2.0.0 of the HL7 Europe Base and Core HL7 FHIR Implementation Guides which are available for both HL7 FHIR R4 and R5. These guides provide a foundational framework to support consistent and interoperable implementations of HL7 FHIR across Europe. They define a common set of base profiles, extensions, and constraints designed to facilitate European initiatives, including the European Health Data Space (EHDS), and to support cross-border health data exchange.
The Base and Core FHIR Implementation Guides are available here:
- HL7 Europe Base and Core IG v2.0.0 HL7 FHIR R4:
https://hl7.eu/fhir/base - HL7 Europe Base and Core IG v2.0.0 HL7 FHIR R5:
https://hl7.eu/fhir/base-r5
Version 2.0.0 represents a significant step forward, incorporating new profiles, references to the latest EHDS-related logical models (Xt-EHR), improved model-to-profile mapping tables, terminology updates, and general publication cleanup.
The HL7 Europe Base and Core Implementation Guides are intended for a wide range of stakeholders, including national programs, healthcare providers, vendors, and research initiatives working on interoperable health data solutions.
By publishing both R4 and R5 versions, HL7 Europe supports the current implementation landscape while preparing the transition towards future HL7 FHIR releases.
The publication of these implementation guides follows the successful ballot and comment period of January 2026, which saw input from 230 individuals, representing 29 countries worldwide, including 23 European countries. This collaborative effort also includes representatives from Xt-EHR Joint Action and MyHealth@EU Solution Providers. The development of this Implementation Guide received support from the xShare and XpanDH projects.
HL7 Europe invites the community to explore the guides, provide feedback, and contribute to their continuous improvement. Contact the HL7 Europe Technical Coordination Team (TNT) at info@hl7europe.org and put “TNT” in the subject line.
About HL7 Europe: HL7 Europe is a not-for-profit Foundation established in Brussels in 2010 with the aim to address European standardisation requirements in digital health serving as the European office of HL7 International. The mission of HL7 Europe is to provide standards that empower global health data interoperability to realise its vision of a world in which everyone can securely access and use the right health data when and where they need it. It works in close cooperation with 23 national HL7 Affiliates across Europe and supports the creation of health information technology standards that are widely and easily used enabling interoperability in healthcare.
